[rndomsrmn]

uBlock and uMatrix are a perfect addition to a setup with a dns based filtering system, though by themselves alone do not provide a solution for all use cases. Think smarttv's, consoles, IOS devices, apps, etc. Basically anything that is not android firefox browser or a desktop browser.

Additionally having DNS filtering in place will also prevent information leakage in case something goes wrong with one of your browser plugins.