It will drain the battery at full load, the i9 is a 45 watt TDP and the RX 5500M is 85 watt TDP (plus display, ram, disk, etc).
However, there's no way the cooling on the laptop can support that much power draw, so I'd expect it to throttle itself way before you'd drain the battery while plugged in.
However, there's no way the cooling on the laptop can support that much power draw, so I'd expect it to throttle itself way before you'd drain the battery while plugged in.