[ankalagon]

According to Encyclopaedia Britannica [1] that's false:

> The city came into existence after the discovery of silver there in 1545 and quickly became famous for its wealth. Within three decades its population surpassed 150,000, making it the largest city in the New World. The population declined from a peak of 160,000 about 1650 as silver production waned, and a typhus epidemic in 1719 claimed the lives of some 22,000 residents. By the early 19th century, Potosí had fewer than 20,000 inhabitants, but the subsequent rise of tin mining again spurred growth.

[1] https://www.britannica.com/place/Potosi-Bolivia