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This is pretty good. I seeded GPT-2 (1.5B) with the first TWO sentences from this biomedical passage [source: https://www.ncbi.nlm.nih.gov/pubmed/19254780 ; I show the remaining original sentences, for comparison to GPT-2]. <start>
Yeast cells lacking the mitochondrial NADH kinase encoded by POS5 display increased sensitivity to hydrogen peroxide, a slow-growth phenotype, reduced mitochondrial function and increased levels of mitochondrial protein oxidation and mtDNA mutations. Here we examined gene expression in pos5Delta cells, comparing these data to those from cells containing deletions of superoxide dismutase-encoding genes SOD1 or SOD2. Surprisingly, stress-response genes were down-regulated in pos5Delta, sod1Delta and sod2Delta cells, implying that cells infer stress levels from mitochondrial activity rather than sensing reactive oxygen species directly. Additionally, pos5Delta, but not sod1 or sod2, cells displayed an anaerobic expression profile, indicating a defect in oxygen sensing that is specific to pos5, and is not a general stress-response. Finally, the pos5Delta expression profile is quite similar to the hap1Delta expression profile previously reported, which may indicate a shared mechanism.
<end> Here is the generated output (following those first two sentences; I needed to do this in Opera; Firefox did not work, possibly due to add-ons and settings). <start>
The results show that POS5Delta cells exhibit decreased expression of two of the genes, SOD1 and SOD2, but increased expression of several other genes, including aldehyde dehydrogenase subunits, NADH dehydrogenase subunits 2 (ODU2), cytochrome c oxidase isoforms (OXO3), and cytochrome b oxidase/OXO1, and increased expression of aldehyde dehydrogenase subunits 1 (ODU1) and 1a2. The results also show that loss of two genes, SOA and SOA1, and two genes, SOA and SOA2, leads to decreased expression of aldehyde dehydrogenase subunits 1, 1a2 and 1a3 and increased expression of ODO1 and ODO1a1. The results show that loss of two genes, ODO2 and ODO1b1, leads to decreased expression of ODO2 and increased expression of O
<end> The output is grammatically / syntactically correct (but o/w nonsensical: e.g. there are no genes ODU1, ODO2 ...). |