[iamcreasy]

The only thing that I need to keep track of is that the idea of no-overlapping windows. The hotkeys behaves differently depending on which windows your mouse is on. Here is a example on the case: C on 3d windows trigger circle select tool, but C on the outliner create a new collection.

But this behavior has exception. Sometimes some keys have global effect. For example, Shift Space always runs the animation.

What other things you find tricky in Blender?

[truckerbill]

One thing I've run into most recently : working with materials is a pain. There's no easy list that you can delete them in a classic-UX way (that I can find). Copying and pasting/duplicating ends up creating large numbers of identical materials and there was no immediately obvious way to prevent this. The interface for creating shared material parameters is unintuitive compared to something like Unreal.

[microcolonel]

You can accomplish it in the Outliner, by searching for "Material". There are other ways, though I guess they could do with some sort of purpose-built view that only exists to list and show materials.