[Andrex]

As a layperson:

Changing genetics seems to me a bit like changing an engine in-flight. Mappping the brain to a computer is more like building a plane from scratch in a hangar.

In a computer, we build the materials but we also build the world around them. With biology, all we have to work with is are the real-life materials, which are harder to grok than their digital equivalents.

[hndamien]

Piece by piece migration/replacement into a computer/ artificial neurons seems more likely. Still a gargantuan task with the requirement of a gargantuan amount of neurons.