[titchard]

This is an interesting project - my first thought would be to flip it, as I am left handed and would benefit from it being oriented that way.

[mkl]

I use trackballs left handed - there are several symmetrical ambidextrous models available. I feel like I'm promoting overly much in this thread, so please just see my other comments for what I use!

[titchard]

I have just found the one you use - will do some research! I do a lot of Fusion 360 work and I always feel like a trackball would help.