And shipping up unrefined ore is also a bit of a ludicrous idea for mass reasons and the rocket equation alone. You do realize you can isolate a nuclear reactor core from explosions on rockets right? What catastrophic failures are you attempting to design your solution of avoiding a nuclear reactor around?
The moon's dust contains huge amounts of helium-3.
Which apparently is an amazing power source.
Also, why fission? We do have working fusion reactors. They are called hydrogen bombs. (The outer part, at least.) As long as you can keep the G forces low ...