Azure has started investing heavily in offloading the task from CPU to GPU and FPGA. There are really good framework on .NET to achieve the same.
NVIDIA CUDA GPU - https://devblogs.nvidia.com/hybridizer-csharp/
GPU scripting and CUDA - http://www.aleagpu.com/release/3_0_4/doc/
FPGA - https://hastlayer.com/project, https://netfpga.org/site/#/