[yason]

Backtick is a bit far away, isn't it? I literally have to stretch my left ring finger to hit it, so doing this for each tmux key command does add up I suppose?

I've been using C-z for the prefix for ages. It's conveniently nearly under the default position where my fingers lay and it also masks the mostly useless suspend signal which I seemed to accidentally hit every now and then. (If I really want to suspend my program 'C-z z' will do just fine.)

Switching around using, for example, C-z C-n/C-p is pretty fast to key in. You can keep ctrl down for support and then it reduces down to typing 'zn' / 'zp'. YMMV.

[spraak]

Ah you're right, I forgot that the keyboard I use isn't common/standard. Backtick is right above Q for me.