[ticmasta]

The short answer is yes.

How you approach this is very dependent on where you're coming from (i.e. existing solution) but with WPF and Winforms now part of Core 3.0 you can then build a native, single exe by specifying the target architecture (ex: win x64) and then bundling the framework with your app. They do some trimming as well (i.e. tree shaking) to get the exe size down but have admitted it's still in early stages and sometimes drops required framework components. You can fix this by adding an explicit reference to the assembly in your project source though...

There are a million ways to get onto different platforms though, ranging from the above, to xamarin to electron (via blazor), to net-new apps, etc.