[alecmg]

Illumina has been stuck at 1000$ per human genome for a while.

New methods are already here, long read sequencing direct from source with minimal preparation [0]. It doesn't say much about cost, but considering reduced preparation step and smaller equipment it should be a fraction of Illumina.

[0] https://www.nature.com/articles/nbt.4125

[lkirk]

Nanopore sequencers may require less prep and may be cheaper, but their sequencing error rate is astronomical, so you'd end up doing a lot more sequencing of the same material before you reached a consensus sequence.

[DoctorOetker]

I believe the nanopore sequencers would fare a lot better if the parasitic capacitance across the membrane could be minimized, by decreasing their surface area, alternatively fluorescent readout of the pore itself

[waiquoo]

https://iopscience.iop.org/article/10.1088/0957-4484/27/7/07...