Don't forget that the US's rapid access to all the healthcare the patient wants leads to huge amounts of harm in the form of over-testing, over-diagnosis, and over-treatment.
Take 1000 men over 50 and give them PSA screening for prostate cancer for about 11 years.
Take 1000 different men over 50 and don't give them PSA screening for prostate cancer for about 11 years.
For the group without screening about 7 die from prostate cancer. But for the group who do have screening we see the same number of deaths. The screening hasn't prevented deaths from prostate cancer.
The group without screening didn't have any false alarms and didn't have any needless biopsies. 160 men in the group with screening had false alarms and unnecessary biopsies. 20 men in the screening group had treatment (which can include incontinence and impotence) for non-progressive prostate cancer.
It absolutely can be. The reason you don’t get colonoscopies until you’re in you’re 40s isn’t because they’re not fun. It’s because the risk of a false positive times the negative consequences thereof outweighs the benefit of you finding something early. People are wierd gooey lumps of random stuff. Scan anyone and you’ll find something out of place. The vast majority is irrelevant until some break even point where it’s not. Hence the recommendations and guidelines.