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by fc_barnes 2468 days ago
Nobody has 0 intake, that is a useless control; nor would any IRB sign off on such a study, because it would be harmful to the subjects.
4 comments

> Nobody has 0 intake

And thus we have ourselves a quandary, but truth isn't diminished by the practical limits of safe experimentation. We don't have to lie just because.

> it would be harmful to the subjects.

That doesn't make the title precise or the observation inapt.

The experiment itself may be useless control; most people get D vitamins from the sun. How do we know the cohorts got the same D from sun exposure?
Should use a blood tests for vitamin D status, probably calcium, phosphate and K too instead of relying on self reported diet.
If you avoid animal foods the only dietary vitamin D really is from fortified products. However we also synthesize it, albeit poorly as adults, particularly with lower exposure to the sun.
Plenty of people have 0 supplementation though.