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by goatsi
2471 days ago
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3) Users take the same amount of heroin with the same purity as previous cases, but combine it with other CNS depressants and die. This was probably the main cause of overdose deaths before fentanyl came along. In one study 45% of the deceased also had a blood alcohol level, and 30% were on Benzodiazepines (one Swedish study had benzos present in 55% of fatal overdoses). https://sci-hub.se/10.1080/09595239996743 >The majority of cases involved heroin in combination with other drugs: alcohol (40%), benzodiazepines (30%)and antidepressants (9%). In only a third of cases was morphine the sole drug detected. https://sci-hub.se/10.1046/j.1360-0443.1996.911217652.x >Fatalities involving only heroin appear to form a minority of overdose occasions, the presence of other drugs (primarily central nervous system depressants such as alcohol and benzodiazepines) being commonly detected at autopsy. |
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