[ken]

With Clojure, the answer is straightforward: here's a jar (or war), or some JS. It's no worse than mainstream languages like Java -- and much better, if you might also need to target JS.

Everyone likes to bash Lisp and Smalltalk for this, but what are you going to do with all your Python/Ruby/Java code if you need to deliver an iOS app? Or target an embedded system, or a game console? Every language has environments where it's difficult or (nearly) impossible to support. It's not unique to those funny languages that don't use curly braces.