[losvedir]

Maybe it's more of a philosophical internal vs external locus of control thing, but I don't find this one similar to tobacco. It's easy to use Dominos and Burger King "responsibly". I don't find anything unethical about their business and wouldn't feel bad working for them.

Tobacco I'm less sure about, since I don't really know of anyone who uses it "responsibly".

[MaximumYComb]

I think it might be different if your boss is telling you to design an advertisement to target 4-8 year olds with junk food ads.

[losvedir]

Not for me, since I don't think it's unreasonable for a 4-8 year old to have Burger King. They just can't have it all the time, but it's a nice treat.