[downandout]

if you are a publisher and have actual content humans care about, ditch the ad networks and start selling your pixels directly to relevant advertisers.

Good luck with direct ad sales, unless you are a large company with a large ad sales team and correspondingly large budget.

[scarface74]

John Gruber’s Daring Fireball and a few other sites seem to be doing okay without a large sales team. He is a one man company.