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by dr_coffee 2502 days ago
The cell's ability to mechanically sense it's surroundings is fascinating. There is an old paper from 2006 in Cell that was similar to this study in that it showed onencould direct stem cell differentiation down different lineages purely by growing the cells on different stiffness substrates. Definitely worth a read of you are interested in this topic:

https://www.ncbi.nlm.nih.gov/m/pubmed/16923388/