[lvl4x]

You probably won't have the option to store your playlists locally though, and streaming music with mobile net could get expensive. The other big apps without good mobile web versions are Whatsapp, Signal, and Telegram. Those could be show-stoppers for some people.

[chupasaurus]

Telegram Desktop would run fine on Librem 5 on Plasma Mobile (magic of QT) and clunky on Gnome (but I might be wrong), as well as APKs on Android emulator like Anbox.