[ska]

No, the problem is work up rate. If you significantly increase the rate of biopsy (typically one of the possible next steps) eventually you are going to kill people, as biopsy is not a zero risk procedure.

You have to be really careful with FP rates in screening. Of course the answer to this could just be "don't biopsy due to only this result" but at some point that renders the approach pointless, if you can't find a cost effective way of mitigating the FPR.