Besides actual issues with mental health history, is there any way to know if someone will react this way to LSD? Set and setting may not be enough in these cases, it seems?
One would likely want to be unafraid of letting go. After a heroic dose like that, it's possible he had some things on his mind and the chemical inescapably brought these things to the forefront of his attention.
Assuming this was pure LSD, 4 full doses is way too much. It leads me wonder if he knew what we was getting into ahead of time or if he was peer pressured and did not have much experience.
The trial will be interesting here. I think his best defense is that he had no clue what a safe dose was and had 0 control over his own actions while he did what he did.
Idk what the sitter situation was but it sounds like this got out of hand pretty fast. If they couldn't calm him I imagine the best they could do is pin him down and tie him up.
More info here: https://erowid.org/experiences/subs/exp_LSD.shtml