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Tobacco is very good at clearing things from the body, like drugs or caffeine. Smokers clear caffeine faster from the brain than non smokers.

Check out the P450 group of enzymes to find out how this works, part of the clearance rate is controlled by the liver becoming more efficient and altering your food and drink cravings.

Other foods/chemicals like grapefruit juice slow the metabolism of some drugs, so 2litres of grapefruit juice combined with 50Mg of viagra will see you visiting A&E with a 5hr priaprism, that has to be let down with andrenaline injections into the corpus spongiosum.

Generally if you want your illegal drugs to last longer dont smoke.