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by olliej 2552 days ago
The highly competent researchers have to answer the question:

“why have the number of children diagnosed with ASD increased?”

They can’t “control” for changing diagnostic rules: that would literally mean “controlling” the exact thing they’re trying to analyze.

What they are doing (as medicinal chemists?) is identify a compound(s) that correlate with the increased diagnoses.

Another study might investigate the method by which ASD is diagnosed - eg applying modern diagnoses to old diagnoses, and vice versa.

There are also definitely sociological factors that could contribute - in the US specialized educational support for kids diagnosed with ASD is much better funded per-capita than most other learning difficulties, so there is a clear advantage to pushing for (or shopping around for) a dr that will give an ASD diagnosis - eg If you can get FAS diagnoses as ASD you’ll get much more financial and educational support.

Personally I expect there to be a parental age component (which would explain the increased prevalence, relative to overall average, of ASD in middle and upper class Caucasian families, at least in the US).

I suspect however it’s going to be a combination of all those factors, and probably a few more for good measure.