[lliamander]

Immunotherapy is really fascinating, I know someone going through it right now and it seems to be helping (early days yet, of course).

I was very curious to read that it had such severe side-effects, especially the neurotoxicity. Why such a severe reaction? Does the neurotoxicity have developmental impacts for children that receive immunotherapy?

[dannykwells]

The origin of CNS toxicity is still a topic of research. I believe it can occur in children as well (I am not an MD and specialize more in the checkpoint inhibitor side of things).