[Madmallard]

Ask your father about drug induced mitochondrial dysfunction. I had ciprofloxacin 4 years ago and my exercise tolerance swiftly dropped in the months afterward. Research tells me this is due to mtdna depletion and dna damage and I just want to know how to get better. I now have stage 1 diastolic dysfunction and a plethora of seemingly unrelated problems, coming from none before.

[AstralStorm]

It's probably not fixable if it's really that. Even if mtDNA is fine the mitochondria have their own mechanism for senescence based on other damage, just like cells. It does not even have to be caused by radicals.

[Madmallard]

Why wouldn't it be fixable?

And would there be a way you think to test if that's really the case?

I have talked with some people who had like severe reactions to the drug who managed to get some kind of mitochondria testing and it would say stuff like "30% of the active sites are blocked on the mitochondria"