[Kalium]

You're right: the risks are both high and uncertain.

With that in mind, it's perhaps worth considering the potential benefits of having a uniform framework for evaluating risks that are attendant upon any given possible course of action. Risk evaluation neither starts nor stops with personal ick-factor or the worst scenarios imaginable. Risk evaluations also need to include the probability of success, expected costs, the estimated probability of any negative outcomes or side-effects, and so on. It's a non-trivial endeavor.

Again, you're right. The risks of any possible course of action, particularly poorly understood ones, are very real. They demand meticulous and systematic evaluation.