[Baeocystin]

I think Asimov's The Relativity of Wrong applies here.

( https://chem.tufts.edu/AnswersInScience/RelativityofWrong.ht... , it is an enjoyable essay to read. )

You are correct that flaws and surprises lurk in all human endeavors. But that does not mean that all potential errors are in the same scale or class. We do not know everything, but we know far more than nothing!