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by jmhmd
2591 days ago
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Regarding gadolinium, linear agents are almost never used anymore (and shouldn't be), at least in the US. Also, macrocyclics do also deposit in your brain in very small amounts, however there has never been any negative effect from this shown to date. And lastly, gadolinium is not known to cause any kidney damage. The problem in the past (in particular with linear agents) was nephrogenic systemic fibrosis, which was shown to occur in patients with pre-existing poor kidney function, probably as a result of being unable to quickly clear the gadolinium, which could then deposit in tissues. There is very little risk (if any) of NSF with newer macrocyclic agents. |
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