[revvx]

I think you have answered your own question: it's one less thing to worry about in your stack.

If you're targeting modern evergreen browsers you already have a lot of modern features at your disposal, including ES6 modules, async/await, string interpolation, but we're not using them.

In fact, I'd say that it's way more than "one thing" that you can stop worrying about: you won't need Webpack/Rollup/etc, Babel, NPM/Yarn, Node.js itself, etc.