I upgraded a VMWare ESXi server hosting FreeNAS from a consumer motherboard with an Intel Core i7 3930K and it was completely painless.
[0]: https://www.asrockrack.com/general/productdetail.asp?Model=E...
[1]: https://www.amd.com/en/products/cpu/amd-epyc-7281
My current HP home-server has been with me for ~10years
My current HP home-server has been with me for ~10years