[terrykfwong]

Thank you for this detail and useful guide Andy.

[andy-thomason]

Thanks, Terry.

I hope it was useful. It is just an introductory jargon-free guide. You can find more on Ensembl and Wikipedia.

[inciampati]

There are a lot of caveats in representing a genome as some point diffs from a reference. I worry that your description might promote a way of thinking about genomes that ignores the more complex things that can and do happen.