Another vote for newsblur (not affiliated, just a satisfied paying customer).
Other than being a generally well-designed feed reader, my favorite feature is that you can configure it - on a feed by feed basis - to render the post website itself (which it trims down to the specific post), rather than the snippet - so with (at most) one click per subscribed feed, I read all the articles inside my feed reader, whether the RSS feed contains an entire article or just a snippet + "click here for more".
I'm a happy Newsblur subscriber. The developer has continued to extend and improve it since the days when he was suddenly mobbed by Google Reader refugees like me. It's got great uptime, I've hardly ever had an issue with it.
Newsblur did add (somewhat recently) a "tiles" like view for graphic/image blogs to the web version. Newsblur might not always be the fastest at picking up hip new features, but I find that Samuel is pretty reliable about eventually adding the "greatest hits" of what everybody else has been doing.
It's also open source for those that want to try to directly contribute code fixes/ideas, but I've rarely felt that need. I'm happy enough just paying the Premium subscription every year and knowing that suggestions on the forums (used to be UserVoice, now is Discourse) get responses pretty quick.
I'd really like a way to "shuffle" stories, such that if, say, CNN pushes out 10 stories and the Guardian pushes out 10 stories 15m later, that the order of presentation shuffles the two of them instead of just showing one source.
Also, link deduplication, because sometimes articles from the e.g. the CNN Politics RSS overlap with the CNN US RSS
Other than being a generally well-designed feed reader, my favorite feature is that you can configure it - on a feed by feed basis - to render the post website itself (which it trims down to the specific post), rather than the snippet - so with (at most) one click per subscribed feed, I read all the articles inside my feed reader, whether the RSS feed contains an entire article or just a snippet + "click here for more".