Hacker News new | ask | show | jobs
by droningparrot 2602 days ago
This is such an interesting insight into how urban planning decisions can affect health.

What are the chances that airborne allergens increase rates of food allergies?

1 comments

As I understand it, very small.

Most allergens are denatured by acid and enzymes in the stomach. Many food allergies, which typically are not the same kind of immunological reaction as seasonal allergies/allergic rhinitis, are caused more by the failure of epidermal barriers or acid attack than by mere exposure. don't become sensitized because you ate something so much as because your body allowed bits to get somewhere they are not allowed to be under any circumstances, which is why the outsized anaphylactic reaction food allergies often cause.

(...typically. In some cases it is cross reaction, where an antigen in food is too similar to some other antigen the body has previously identified as an invader. See for example the temporary meat allergy that can be caused by some Lone Star tick bites. And there are yet other causes of course...)

Seasonal allergies are usually mild because they are generally localized, peripheral, and provoked in tissues that are designed to give this response as a normal protective action.

(That is, your nose is correct to run or stuff in response to histamine release caused by pollen. Frankly, I feel some foreboding about what sequelae we will eventually discover to be caused by chronic H2 antagonist administration over decades, drugs like Claritin/Zyrtec that people are taking every day of their lives.)

So! While it is possible and some rare cross reactions have been observed (particularly in fruiting trees/eating fruits), as a general rule your seasonal allergies do not increase your food allergy risk.

Now, some people are at higher risk for both due to environmental or genetic circumstances. But there it is a prior immune dysfunction that caused both rather than one causing the other-- though it's an understandable intuition to connect them as your question does. Having one or the other makes it more likely you have both, but it one doesn't cause the other.

>So! While it is possible and some rare cross reactions have been observed (particularly in fruiting trees/eating fruits), as a general rule your seasonal allergies do not increase your food allergy risk.

If you're talking about oral allergy syndrome, it isn't really what I'd call rare.