[IggleSniggle]

The unique part about computation is that we can throw an immense amount of energy at specific problems in isolation to force rapid evolution, and backtrack to snapshots easily if we don’t like where we ended up.

You can select for an intelligent swarm of fruit-flies, but it’s going to take you a lot longer to get your result than if you could simulate the whole process. Now, if it’s simulated, will you be able to walk your final result back to meat-world DNA? Not unless you included that level of detail in your simulation, which would be extraordinarily expensive to do and fraught with problems due to the scale. But even then, the simulation gives you some advantages: affect the flow of time, backtrack in time to explore other paths under alternate simulated conditions, etc. In the real world, you can’t have that kind of perfect reproducibility.