[tropo]

Wyoming, and any state rounded up to 1 representative, is special. Aside from that the effect is minor.

There is an effect going the other direction that benefits California, and in fact is why there is a fight going on at the Supreme Court. Voters in those rural states are underrepresented due to non-citizens being counted to apportion the representatives. California has something like a couple dozen extra representatives from that.

[nradov]

The effects of Wyoming having two senators are far from minor in an age where key votes have been decided on a 51-49 basis.