[beetwenty]

My observation from having tested the three most common isomorphic systems with PC keybindings is that the Janko-style mapping(which I believe is the default mapping of Chromatone) is the most familiar to piano players, and the least disruptive in terms of playstyle. Harmonic Table is at the other extreme - it minimizes note distances to the point where ergonomics for traditional playing are hampered - chromatics are downright uncomfortable, but you can easily reel off huge jumps around the scale that would otherwise require virtuosic technique. Wicki-Hayden sits somewhere in between those two.