[tetraca]

That nothing matters at all in a grand scale frees you from the burden of having to matter. No legacy, no contribution, will ever be capable of cementing you into the permanent fabric of the universe. The most powerful human and all that he has done, is as meaningless as the most helpless and shortest lived; when the last historian dies even Caesar's name shall be dust. Your life effectively has no lasting consequences, so try and do what you actually wish.

I don't personally subscribe to such a worldview but lots of people will find freedom or comfort in that.