[tigershark]

I found that the most problems are for the eyes, if the monitors take too much of your FOV. I worked in the past with 8 monitors and after a while it really impairs my ability to focus far away. Luckily it seems reversible after several months, especially if you spend a lot of time outside looking far away.

[walterbell]

You can place monitors at different distances from your eyes. Screen resolution can be changed to maintain perceived relative size of onscreen objects.

For eye health, have the monitors backing a window (or 20+ feet of empty space), so that you can periodically (at least every 20 minutes) look past the monitors at an "infinite" plane.

[tigershark]

It’s not practical in an open office with everything standardised. Sure in an Home Office you can do pretty much what you want if you have enough space.

[walterbell]

You can at least position the laptop closer than the monitor, which gives you two focal planes. In an open office, there should be many "distant" objects to use as a temporary third focal plane.

[nitrogen]

I brought my own clamp-on monitor arms to the open office I work in and installed them myself without asking anyone. You might be able to get away with the same.