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Calculator is interesting in that there is a physical button on (many) keyboards to open it. Ironically enough, I encountered a bug with the Windows 10 calculator that caused it to crash upon opening: the window would draw, then a second later vanish.

Turned out that it was due to something profile related: re-registering the Windows App Store fixed the issue. Yes, that's right, a dependency on the app store can prevent you from running Calculator.