Beware! You entered the "cutesy animals, let's save the planet, everyone's cool man" territory with nuance, humour and wider perspective. People don't forgive that easily.
If you want to be fun at parties, you can also try this: "What do you mean, 'YOLO, do what your heart tells you, no matter what they say'? Does that also apply to rapists and murderers?"
I'll make an exception for infectious diseases... certainly getting rid of smallpox was, and eventually getting rid of HIV will be, a cause for celebration.
If you want to be fun at parties, you can also try this: "What do you mean, 'YOLO, do what your heart tells you, no matter what they say'? Does that also apply to rapists and murderers?"