[ColinWright]

I use Zim wiki for notes, with a suitable SOP for making sure things float to the top when needed. I also have a script that crawls over the pages searching for "REMIND" lines, and sets reminders.

So in essence, Zim for notes, and a couple of scripts that reads the underlying pages and takes appropriate actions.

Heavily tailored to be exactly and only what I want, but easily extensible when needed.