Not out of the box, no. The FreeNAS implementation (and I assume many others) depends on rclone [1], which describes it as rsync for cloud providers.
For protection against that you would have to implement periodic snapshots (which many NAS products also support) and sync the snapshots. Or you could probably use B2's built in snapshot feature. Both require additional manual work, though.
For protection against that you would have to implement periodic snapshots (which many NAS products also support) and sync the snapshots. Or you could probably use B2's built in snapshot feature. Both require additional manual work, though.
[1]: https://rclone.org/