There would be an entire new dimension of decision making, in addition to good macro, where you have to prioritize actions. Will be interesting to see.
I said so before, but is it really a big difference from controlling a unit that can also only do one thing at a time? The agent controls itself just like another unit, with a constraint on APM available to control other units. On the one hand, these APMs add a new parameter, if the constraint is implemented naively. On the other hand, if there are viable strategies against ultrahigh APM opponents, then the constrained is really rather limiting the dimensions of the decision space and to good effect, finding viable strategies that take less effort. Hence such things are called "hyperparameters" (I think that's something different, but you know what I mean). Likewise, the game isn't as fast as to need 100 screen switches per second, if good planning allows batching and bursting actions.