[SeaDude]

I really want the things Guix provides, but I'm not a computer scientist. Feels like you need to be to make it work somewhat like the linux desktop I enjoy computing on (text editor, graphical web browser, sky, virtualbox, postman, osb, keepassxc, etc.)

[Ambrevar]

If you look at https://guix-hpc.bordeaux.inria.fr/browse? you'll find most of your wishes there, and many more to come hopefully.

Guix is also working on an installer to help reducing the friction. I'd personally like to work on a fully graphical install + package management.

While Guix sounds like some heavy scientific stuff, it really is a powerful base that allows anything to grow on top, including user-friendly interfaces.

[rekado]

I'm one of the Guix co-maintainers and a Guix user, but I'm not a computer scientist.

The biggest thing that might be annoying for someone who is not comfortable with Lisp is probably the operating system configuration, which is done with Scheme. For installing packages, however, you can use the command line interface, or the convenient Emacs user interface --- neither of those require any programming knowledge.

[AnIdiotOnTheNet]

Sadly the innovation in Guix and Nix is to bring even more complication what should be the straight-forward task of getting software on your machine, not less.