[pjscott]

Quitting emacs should be a fairly rare task; just remap C-x C-c to something harder to hit by accident in your .emacs file.

(I would do this myself, but I keep putting it off.)

[jrockway]

Oh, I do. Same with C-z as mentioned below. When I'm in a terminal-based session, I keep C-x C-c and C-z around. When I'm in my main X-based session, C-z is zap-to-char and C-x C-c is bury-buffer.