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by DanBC 2733 days ago
> In fact, paracetamol poisoning is the primary cause of death in overdoses (in the US, UK, Australia and New Zealand)[2].

No, it isn't, and for the people who die from paracetamol it's an intentional overdose, it's very rarely an accidental overdose.

In the US about 500 people die each year from acetaminophen overdose per year, compared to over 70,000 from opioids.

Your link number 3 is talking about compounds containing paracetamol. For example, this includes coproxamol. Anyone overdosing on coproxamol was dying from the opioid (dextropropoxyphene), not from the paracetamol.

In the UK we have the ONS deaths related to drugs poisoning. Figure six shows deaths compared by drug type, and paracetamol clear isn't the highest: https://www.ons.gov.uk/peoplepopulationandcommunity/birthsde...

We also have the NCISH data. Item 120 here: https://documents.manchester.ac.uk/display.aspx?DocID=38469

3095 deaths by self-poisoning.

    Substance                    Number   
  Opiates/opioids                 947    33%
  - opiates only                  746    26%
  - paracetamol/opiate compound   201     7%
  Non-opiate analgesics           205     7%
  Antipsychotics                  302    11%
  Antidepressants                 587    21%
  - tricyclics                    271     9%
  - SSRI/SNRIs                    260     9%
  - other antidepressants          56     2%

Paracetamol is dangerous in overdose, but that says nothing about its safety in normal usage.