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by emilburzo 2751 days ago
Allow me to offer a different perspective: I've used 23andme and it was one of the best decisions ever.

Not so much for the Ancestry part, which was also interesting and explained my above-average cold tolerance, but for the health stuff.

Granted, being from Europe they don't directly offer health services, but you can get the raw data and upload it to various sites for interpretation -- ranging from really accessible to follow-the-rabbit-hole style.

I've accepted from the start that everything is uncertain, or just a possibility, but it was still very useful, because I knew what to look for and thus able to validate easily if true or not.

Some things that were in the reports I already knew, some I suspected, some I had no idea and would have never guessed -- this last group had the most impact.

Some examples: allergies, motion sickness, needing above average amounts of vitamin C.

All very easy to test, but with an amazing quality of life improvement gained as a result of just changing some simple things.

So yes, a US company has my personal DNA data, maybe they will take care of my privacy, maybe not, but the quality of life gains were worth it, for me.

What other alternative would people like me have, from countries where there is no access to good doctors, of finding stuff like that, had there not been 23andme? Especially since I didn't even know what I was looking for.

4 comments

That's a very good and level headed response to the parent. I agree with both perspectives. I think the crucial point is that you seem to have thought through the implications of deciding for or against using 23andme and after weighing the outcomes, you made an educated decision. Perhaps the decision was right (fingers crossed), maybe it was wrong, but the important point is that you thought about it.

I took parent's post less as a blanket warning against doing DNA tests, and more of a caution to consider the implications.

I think there is value in services like 23andme, and even if there are risks that the information will be misused, the risks are worth it. I don't mean the risks associated with case of a specific person, but the research and services associated with DNA sequencing in general.

Maybe 23andme is not the way forward, and eventually some other (better) services will arise, but we (humanity) are in something of an uncharted territory here, so there is need for a bit of trial and error. Yes there be dragons, and occasionally we'll have our eyebrows singed, but advances in medicine and biology (as your case highlights) are vast.

Since you are from Europe, shouldn't you be able to use GDPR on them?
Good idea, I hadn't thought of that.

Looks like they even have a nice page about it: https://www.23andme.com/gdpr/

What sites did you use ? I used promethease site, but it was way too much information, and the filters felt complicated. Is there any other site that makes a better job filtering what is more important for you specifically ? Any recommendation ?
Here's a list of sites I've tried: https://www.reddit.com/r/23andme/comments/9l50k5/a_list_of_t...

They're all pretty interesting, but the most impactul (read: actionable reports), for me, was: https://www.xcode.life/

[No affiliation, I didn't even get a discount :(]

> explained my above average cold tolerance ... I knew what to look for...

Sorry but this makes it sound like horoscope reading.

If you can't rely on it to make predictions and only use it to confirm preexisting ideas about yourself how is it better than pseudoscience?

I don't follow / maybe what I meant got lost in language.

To rephrase:

- there were some things in the report that I already knew, it was nice to see confirmation -> points++

- there were some things in the report that I suspected, but wasn't sure about, also nice to see it written black-on-white -> points++

- there were some things in the report which I had no clue about, but were easy to test if they are true or not (they were) -> points++++++++++++++

And to keep it fair: there were also things which didn't really apply at all.

But my point was, because I knew what to observe better, it was easy to keep the relevant stuff and ignore the rest.

I have always been "sickly." Getting my genetic disorder properly identified was amazingly empowering and life changing in the most positive way.