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by reasonattlm
2755 days ago
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The article falls a little far on the side of saying there is nothing wrong with a 60-something year old. There is a lot wrong with a 60-something year old. It might not yet rise to the level of constant debilitating pain and loss of basic function, but it is there, and accelerating. The high-functioning 60-something doesn't have great odds of becoming a high-functioning 70-something, or of continuing to evade cancer. If a 20-year old had the skin and cardiovascular system of a high functioning 60 year old, they would be in and out of the hospital, and undergoing serious therapy to prevent a predicted death in their 30s. Rejuvenation therapies are best applied in advance, when the damage of aging is low. Don't play the game of saying that a 60-something who can walk around without a cane is just fine. They are not just fine. They are candidates for every form of therapy we can build that repairs the molecular damage of aging. Every 60-year should be taking senolytics today, right now, for example. Their good-for-a-60-year-old metrics would be greatly improved by doing so. |
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Are you joking? Senolytics have not been proven to work in humans yet. Only in mice. And there's a large, very large literature of drugs that don't work at all the same way in mice and humans.
It reminds me of the DHEA that was touted as a miracle drug for seniors back in the 90s, and the completely failed to meet any expectation.