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Because people who didn't ever taken a drug have never felt nearly this bright and this happy and such intensity of pleasant feelings and mental capacity is far outside of boundaries of their imagination. Once an addiction-prone person experiences that it's possible they will never want to feel ordinary again. Also, if they do it wrong (and they usually do, unfortunately so many people choosing to try drugs don't care to do research nor to spare money on supplements that are going to protect their health during the experience and help to recover after it) they are going to experience hangover caused by their body resources depletion and receptors disregulation, feel particularly bad and hurry to fix this with just another dose of the same substance taken the same (or even worse) way that caused that. I took the way depicted in the "limitless" movie (not to the point of becoming a politician :-) though) and given it up completely shortly after (as I prefer the normal state and don't really like to stress myself and undermine my health that way) but many people who are less rationally-minded, less psychologically-developed and have less-satisfying lives just go junky and I believe many of them could be saved by just being educated (not scared) better. I really don't recommend anybody to try drugs but whoever already takes them or is going to do anyway - search trough and read the darn Reddit, Quora etc thoroughly!

It is also important to emphasize that that's about just a single class of drugs you've mentioned. Popular psychedelics, although able to induce even stronger sensations usually don't cause even psychological addiction (although there are some rare people who start taking them every weekend, a normal person will hardly feel like repeating the experience soon and any kind of regular - it's just too intense psychologically and there also is tolerance, the acid wears off in some hours and won't really work until the next week) and (except some of them) hardly cause any harm (unless you're a psycho already - then you may happen to go nuts completely) or hangover. Opiates, at the same time, don't make you bright but just give a strong sense of relief kind of "I just feel good and uck everything absolutely" yet cause powerful physiological addiction, severe hangovers and serious risk of lethal overdose.